Article
Genetic association study of the HLA class II alleles DRB1, DQA1, and DQB1 in patients with pharmacoresistant temporal lobe epilepsy associated with mesial hippocampal sclerosis.
Seizure - 1 Sept 2015
Horta Wagner G, Paradela Eduardo, Figueiredo André, Meira Isabella D'Andrea, Pereira Valéria C Santa Rita, Rego Cláudia C, Oliveira Raquel, Andraus Maria Emilia C, de Lacerda Glenda C Borges, Moura Polyana, de Souza Jorge P Marcondes, Paiva Carmen Lucia A, Alves-Leon Soniza V
Abstract excerpt
PURPOSE: Temporal lobe epilepsy (TLE) is the most common variety of focal epilepsy among adults. The neuroinflammatory mechanisms of epilepsies may be involved in the genesis of seizures and refractory epilepsies, particularly in the case of progressive syndromes such as TLE associated with mesial hippocampal sclerosis (TLE-HS). The goal of the present study is investigate the genetic profile of susceptibility of...
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