Article
Molecular analysis of HLA class II-associated susceptibility to neuroinflammatory diseases in Korean children.
Journal of Korean medical science - 1 Jun 2004
Oh Hyun Hee, Kwon Soon Hak, Kim Chang Woo, Choe Byung Ho, Ko Cheol Woo, Jung Hee Du, Suh Jang Soo, Lee Jun Hwa
Abstract excerpt
The work was done to study immunogenetic peculiarities of neuroinflammatory diseases among Korean children. A total of 13 children with neuroinflammatory diseases (8 males and 5 females; mean age 4.6 +/-2.6 yr) were consecutively recruited. Geno-mic typing was performed on their HLA DRB/HLA DQB genes using PCR-SSOP/SSP techniques with gel immunoelectrophoresis. The frequencies of HLA-DR1 *15 in children with...
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