Article
The genetic link between systemic autoimmune disorders and temporal lobe epilepsy: A bioinformatics study.
Epilepsia open - 1 Jun 2023
Malekpour Mahdi, Salarikia Seyed Reza, Kashkooli Mohammad, Asadi-Pooya Ali A
Abstract excerpt
OBJECTIVE: We aimed to explore the underlying pathomechanisms of the comorbidity between three common systemic autoimmune disorders (SADs) [i.e., insulin-dependent diabetes mellitus (IDDM), systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA)] and temporal lobe epilepsy (TLE), using bioinformatics tools. We hypothesized that there are shared genetic variations among these four conditions. METHODS:...
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