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Article

Immunogenetic protective factors in Genetic Generalized Epilepsy.

Epilepsy research - 1 Oct 2020

Chaves João, Martins-Ferreira Ricardo, Ferreira Ana Marta, Brás Sandra, Carvalho Cláudia, Bettencourt Andreia, Samões Raquel, Monteiro Fábio, Freitas Joel, Chorão Rui, Lopes João, Ramalheira João, da Silva Berta Martins, Costa Paulo Pinho, da Silva António Martins, Leal Bárbara

Abstract excerpt

BACKGROUND: Genetic Generalized Epilepsies (GGEs) are a heterogeneous group of syndromes characterized by generalized seizure activity that affects both hemispheres, with mainly genetic causes. Neuroinflammation has been established as an important mechanism in epileptogenesis. The ability to develop an appropriated immune response is strongly determined by immunogenetic factors. In this setting, our aim was to...

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PMID: 32585211
DOI: 10.1016/j.eplepsyres.2020.106396

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