Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of non-HLA genes with type 1 diabetes autoimmunity.

Diabetes - 1 Aug 2005

Steck Andrea K, Bugawan Teodorica L, Valdes Ana Maria, Emery Lisa M, Blair Alan, Norris Jill M, Redondo Maria J, Babu Sunanda R, Erlich Henry A, Eisenbarth George S, Rewers Marian J

Abstract excerpt

Approximately 50% of the genetic risk for type 1 diabetes is attributable to the HLA region. We evaluated associations between candidate genes outside the HLA region-INS, cytotoxic T-lymphocyte-associated antigen (CTLA)-4, interleukin (IL)-4, IL-4R, and IL-13 and islet autoimmunity among children participating in the Diabetes Autoimmunity Study in the Young (DAISY). Children with persistent islet autoantibody...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Differentiation
Share to Autoimmunity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CTLA-4 Antigen

Share to Diabetes Mellitus, Type 1

Share to Interleukin-13

Share to Interleukin-4

Share to Islets of Langerhans

Share to Receptors, Interleukin-4

Source

Identifiers

PMID: 16046318
DOI: 10.2337/diabetes.54.8.2482

Genes

INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of non-HLA genes with type 1 diabetes autoimmunity.PMID 16046318Read ↗

Do non-HLA genes influence development of persistent islet autoimmunity and type 1 diabetes in children with high-risk HLA-DR,DQ genotypes?Semantic proximity Read ↗

Effects of non-HLA gene polymorphisms on development of islet autoimmunity and type 1 diabetes in a population with high-risk HLA-DR,DQ genotypes.Semantic proximity Read ↗

Genetics of type 1 diabetes.Semantic proximity Read ↗

rs11203203 is associated with type 1 diabetes risk in population pre-screened for high-risk HLA-DR,DQ genotypes.Semantic proximity Read ↗

Improving prediction of type 1 diabetes by testing non-HLA genetic variants in addition to HLA markers.Semantic proximity Read ↗

A strategy for combining minor genetic susceptibility genes to improve prediction of disease in type 1 diabetes.Semantic proximity Read ↗

Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort.Semantic proximity Read ↗

Associations of polymorphisms in non-HLA loci with autoantibodies at the diagnosis of type 1 diabetes: INS and IKZF4 associate with insulin autoantibodies.Semantic proximity Read ↗

Insulin gene VNTR, CTLA-4 +49A/G and HLA-DQB1 alleles distinguish latent autoimmune diabetes in adults from type 1 diabetes and from type 2 diabetes group.Semantic proximity Read ↗

Non-HLA risk variants in a type 1 diabetes pediatric population: Clinical and autoimmune profiles.Semantic proximity Read ↗

Insulin gene VNTR polymorphisms -2221MspI and -23HphI are associated with type 1 diabetes and latent autoimmune diabetes in adults: a meta-analysis.Semantic proximity Read ↗

Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.