Article
Immunogenicity of Semliki Forest virus based self-amplifying RNA expressing Indian HIV-1C genes in mice.
International journal of biological macromolecules - 1 Nov 2015
Ajbani Seema P, Velhal Shilpa M, Kadam Ravindra B, Patel Vainav V, Bandivdekar Atmaram H
Abstract excerpt
Development of recombinant vaccines is considered as a promising approach to prevent transmission and eradication of HIV/AIDS. Candidate vaccines tested so far have shown poor to modest efficacy. Self-amplifying RNAs of positive strand alphaviruses are reported to be promising vectors for development of recombinant vaccines. This study describes the construction, in vitro expression and in vivo immunogenicity of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
