Article
Structural studies of parkin and sacsin: Mitochondrial dynamics in neurodegenerative diseases.
Movement disorders : official journal of the Movement Disorder Society - 1 Oct 2015
Li Xinlu, Gehring Kalle
Abstract excerpt
Neurodegenerative diseases are prevalent, chronic diseases emanating from the dysfunction or death of neurons. The disrupted mitochondrial dynamics observed in a large number of neurodegenerative diseases suggests a common etiology with the possibility of therapies targeting multiple diseases. This review highlights the contributions of structural studies of disease-related proteins to the understanding of...
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