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Article

Rapid Molecular Detection of Multidrug-Resistant Tuberculosis by PCR-Nucleic Acid Lateral Flow Immunoassay.

PloS one - 1 Jan 2015

Kamphee Hatairat, Chaiprasert Angkana, Prammananan Therdsak, Wiriyachaiporn Natpapas, Kanchanatavee Airin, Dharakul Tararaj

Abstract excerpt

Several existing molecular tests for multidrug-resistant tuberculosis (MDR-TB) are limited by complexity and cost, hindering their widespread application. The objective of this proof of concept study was to develop a simple Nucleic Acid Lateral Flow (NALF) immunoassay as a potential diagnostic alternative, to complement conventional PCR, for the rapid molecular detection of MDR-TB. The NALF device was designed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26355296
DOI: 10.1371/journal.pone.0137791
PMCID: PMC4565584

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