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Two target genes based multiple cross displacement amplification combined with a lateral flow biosensor for the detection of Mycobacterium tuberculosis complex

4 Oct 2021

Abstract excerpt

BACKGROUND: Tuberculosis (TB) is a serious chronic infectious disease caused by Mycobacterium tuberculosis complex (MTBC). Hence, the development of a novel, simple, rapid and sensitive method to detect MTBC is of great significance for the prevention and treatment of TB. RESULTS: In this study, multiple cross displacement amplification (MCDA) combined with a nanoparticle-based lateral flow biosensor (LFB) was...

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Share to Advanced biosensing and bioanalysis techniques
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PMID: 34607556
DOI: 10.1186/s12866-021-02328-6

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