Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

iFIND INH/FQ: a LC-aNAAT assay for rapid simultaneous detection of isoniazid and fluoroquinolone resistance in Mycobacterium tuberculosis.

Microbiology spectrum - 3 Mar 2026

Ou Xichao, Ma Yingzi, Zheng Huiwen, Li Yan, Zeng Jiaojian, Chen Yuying, Huang Lin, Guo Yajie, Zhao Bing, Li Jingjing, Xing Ruida, Xia Hui, Zhao Yanlin

Abstract excerpt

To evaluate the performance of the iFIND INH/FQ, a low-complexity molecular assay, for the rapid and simultaneous detection of resistance to isoniazid (INH) and fluoroquinolones (FQs) in Mycobacterium tuberculosis. Frozen sputum specimens stored at the Chengde Center for Disease Control and Prevention laboratory were used. Phenotypic drug susceptibility testing (pDST) and DNA sequencing served as reference...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antitubercular Agents
Share to Catalase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Gyrase

Share to Fluoroquinolones

Share to Isoniazid

Share to Oxidoreductases

Share to Sputum

Share to Tuberculosis, Multidrug-Resistant

Source

Open in PubMed Open full text

Identifiers

PMID: 41649261
DOI: 10.1128/spectrum.03743-25
PMCID: PMC12955496

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

iFIND INH/FQ: a LC-aNAAT assay for rapid simultaneous detection of isoniazid and fluoroquinolone resistance in Mycobacterium tuberculosis.PMID 41649261Read ↗

Development and preliminary assessment of the iFIND TBR: all-in- one molecular diagnostic assay for rapid detection of Mycobacterium tuberculosis and rifampicin resistance.Semantic proximity Read ↗

Analytical and clinical performance characteristics of the Abbott RealTime MTB RIF/INH Resistance, an assay for the detection of rifampicin and isoniazid resistant Mycobacterium tuberculosis in pulmonary specimens.Semantic proximity Read ↗

Laboratory Evaluation of a Lateral-Flow Cell for Molecular Detection of First-Line and Second-Line Antituberculosis Drug Resistance.Semantic proximity Read ↗

Multi-Fluorescence Real-Time PCR Assay for Detection of RIF and INH Resistance of M. tuberculosisSemantic proximity Read ↗

Off-label evaluation of the BD MAX MDR-TB assay for rapid diagnosis of rifampicin and isoniazid resistance of<i>Mycobacterium tuberculosis</i>clinical isolates in a high-volume reference laboratorySemantic proximity Read ↗

Off-label evaluation of the BD MAX MDR-TB assay for rapid diagnosis of rifampicin and isoniazid resistance of Mycobacterium tuberculosis clinical isolates in a high-volume reference laboratory.Semantic proximity Read ↗

Molecular characterization of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis from the USASemantic proximity Read ↗

Detection of Mycobacterium tuberculosis complex in pulmonary and extrapulmonary samples with the FluoroType MTBDR assay.Semantic proximity Read ↗

NTF-RINT, a new method for the epidemiological surveillance of MDR Mycobacterium tuberculosis L2/Beijing strains.Semantic proximity Read ↗

A cartridge-based assay for improved detection of multidrug-resistant Mycobacterium tuberculosis directly from sputum.Semantic proximity Read ↗

High frequency of isoniazid and fluroquinolone resistance among patients with rifampicin sensitive tuberculosis.Semantic proximity Read ↗

Rapid detection of fluoroquinolone resistance in Mycobacterium tuberculosis using a novel multienzyme isothermal rapid assay.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.