Article
Regulated expression of virulence gene mviN provides protective immunity and colonization control of Salmonella in poultry.
Vaccine - 5 Oct 2015
Rubinelli Peter M, Lee Sang In, Roto Stephanie M, Park Si Hong, Ricke Steven C
Abstract excerpt
Current live attenuated vaccines for control of Salmonella in poultry persist in the ceca and may persist in the environment. In this paper we report the construction and characterization of the vaccine efficacy of a Salmonella mutant strain with inducible mviN expression and rapid clearance from the host. The mutant was effective in oral immunization of the broiler chicken host against a virulent Salmonella oral...
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