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Article

Reveel: large-scale population genotyping using low-coverage sequencing data.

Bioinformatics (Oxford, England) - 1 Jun 2016

Huang Lin, Wang Bo, Chen Ruitang, Bercovici Sivan, Batzoglou Serafim

Abstract excerpt

MOTIVATION: Population low-coverage whole-genome sequencing is rapidly emerging as a prominent approach for discovering genomic variation and genotyping a cohort. This approach combines substantially lower cost than full-coverage sequencing with whole-genome discovery of low-allele frequency variants, to an extent that is not possible with array genotyping or exome sequencing. However, a challenging computational...

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PMID: 26353840
DOI: 10.1093/bioinformatics/btv530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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