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Article

Optimized sample selection for cost-efficient long-read population sequencing.

Genome research - 1 May 2021

Ranallo-Benavidez T Rhyker, Lemmon Zachary, Soyk Sebastian, Aganezov Sergey, Salerno William J, McCoy Rajiv C, Lippman Zachary B, Schatz Michael C, Sedlazeck Fritz J

Abstract excerpt

An increasingly important scenario in population genetics is when a large cohort has been genotyped using a low-resolution approach (e.g., microarrays, exome capture, short-read WGS), from which a few individuals are resequenced using a more comprehensive approach, especially long-read sequencing. The subset of individuals selected should ensure that the captured genetic diversity is fully representative and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33811084
DOI: 10.1101/gr.264879.120
PMCID: PMC8092009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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