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Article

Variant calling in low-coverage whole genome sequencing of a Native American population sample.

BMC genomics - 30 Jan 2014

Bizon Chris, Spiegel Michael, Chasse Scott A, Gizer Ian R, Li Yun, Malc Ewa P, Mieczkowski Piotr A, Sailsbery Josh K, Wang Xiaoshu, Ehlers Cindy L, Wilhelmsen Kirk C

Abstract excerpt

BACKGROUND: The reduction in the cost of sequencing a human genome has led to the use of genotype sampling strategies in order to impute and infer the presence of sequence variants that can then be tested for associations with traits of interest. Low-coverage Whole Genome Sequencing (WGS) is a sampling strategy that overcomes some of the deficiencies seen in fixed content SNP array studies. Linkage-disequilibrium...

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Identifiers

PMID: 24479562
DOI: 10.1186/1471-2164-15-85
PMCID: PMC3914019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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