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Article

Establishment of a novel human embryonic stem cell-derived trophoblastic spheroid implantation model

7 Sept 2015

Abstract excerpt

STUDY QUESTION: Can human embryonic stem cell-derived trophoblastic spheroids be used to study the early stages of implantation? SUMMARY ANSWER: We generated a novel human embryonic stem cell-derived trophoblastic spheroid model mimicking human blastocysts in the early stages of implantation. WHAT IS KNOWN ALREADY: Both human embryos and choriocarcinoma cell line derived spheroids can attach onto endometrial...

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PMID: 26350609
DOI: 10.1093/humrep/dev223

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