Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

3D-cultured blastoids model human embryogenesis from pre-implantation to early gastrulation stages

1 Sept 2023

Abstract excerpt

Naive human pluripotent stem cells have the remarkable ability to self-organize into blastocyst-like structures ("blastoids") that model lineage segregation in the pre-implantation embryo. However, the extent to which blastoids can recapitulate the defining features of human post-implantation development remains unexplored. Here, we report that blastoids cultured on thick three-dimensional (3D) extracellular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Pluripotent Stem Cells Research
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37683602
DOI: 10.1016/j.stem.2023.08.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

3D-cultured blastoids model human embryogenesis from pre-implantation to early gastrulation stagesPMID 37683602Read ↗

Dissecting peri-implantation development using cultured human embryos and embryo-like assembloidsSemantic proximity Read ↗

Modeling human pregastulation development by 3D culture of blastoids generated from primed-to-naïve transitioning intermediatesSemantic proximity Read ↗

Dissecting peri-implantation development using cultured human embryos and embryo-like assembloidsSemantic proximity Read ↗

Human blastoids model blastocyst development and implantationSemantic proximity Read ↗

Transgene-Free Ex Utero Derivation of A Human Post-Implantation Embryo Model Solely from Genetically Unmodified Naïve PSCsSemantic proximity Read ↗

The emergence of human gastrulation upon in vitro attachmentSemantic proximity Read ↗

Complete human day 14 post-implantation embryo models from naive ES cellsSemantic proximity Read ↗

Generation of human blastocyst-like structures by somatic cell reprogrammingSemantic proximity Read ↗

Large scale production of human blastoids amenable to modeling blastocyst development and maternal-fetal crosstalkSemantic proximity Read ↗

The emergence of human gastrulation upon <i>in vitro</i> attachmentSemantic proximity Read ↗

Stem cell models of human embryo implantation and trophoblast invasionSemantic proximity Read ↗

Single-Cell RNA Sequencing Reveals Regulatory Mechanism for Trophoblast Cell-Fate Divergence in Human Peri-Implantation EmbryoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.