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In Vitro Model of Human Trophoblast in Early Placentation

15 Apr 2022

Abstract excerpt

The complex process of placental implantation and development affects trophoblast progenitors and uterine cells through the regulation of transcription factors, cytokines, adhesion receptors and their ligands. Differentiation of trophoblast precursors in the trophectoderm of early ontogenesis, caused by the transcription factors, such as CDX2, TEAD4, Eomes and GATA3, leads to the formation of cytotrophoblast and...

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PMID: 35453654
DOI: 10.3390/biomedicines10040904

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