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Article

The problem of genotype and sex differences in life expectancy in transgenic AD mice.

Neuroscience and biobehavioral reviews - 1 Oct 2015

Rae Eric A, Brown Richard E

Abstract excerpt

The lifespan of mice shows genotype, sex and laboratory effects, but little is known about genotype or sex differences in life expectancy of mouse models of Alzheimer's disease (AD). This paper examines the lifespan of males and females of different mouse models of AD and their wildtype strains. Genotype and sex dependent differences in longevity have important implications for designing experiments with...

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PMID: 26348702
DOI: 10.1016/j.neubiorev.2015.09.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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