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Article

SPINK1 Promoter Variants in Chronic Pancreatitis.

Pancreas - 1 Jan 2016

Hegyi Eszter, Geisz Andrea, Sahin-Tóth Miklós, Derikx Monique H M, Németh Balázs Csaba, Balázs Anita, Hritz István, Izbéki Ferenc, Halász Adrienn, Párniczky Andrea, Takács Tamás, Kelemen Dezső, Sarlós Patrícia, Hegyi Péter, Czakó László

Abstract excerpt

OBJECTIVES: Serine protease inhibitor Kazal type 1 (SPINK1) provides an important line of defense against premature trypsinogen activation within the pancreas. Our aim was to identify pathogenic SPINK1 promoter variants associated with chronic pancreatitis (CP). METHODS: One hundred CP patients (cases) and 100 controls with no pancreatic disease from the Hungarian National Pancreas Registry were enrolled. Direct...

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Identifiers

PMID: 26348468
DOI: 10.1097/MPA.0000000000000412

Genes

SPINK1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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