Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TNFAIP2 Inhibits Early TNFα-Induced NF-x03BA;B Signaling and Decreases Survival in Septic Shock Patients.

Journal of innate immunity - 1 Jan 2016

Thair Simone A, Topchiy Elena, Boyd John H, Cirstea Mihai, Wang Catherine, Nakada Taka-Aki, Fjell Christopher D, Wurfel Mark, Russell James A, Walley Keith R

Abstract excerpt

During septic shock, tumor necrosis factor alpha (TNFα) is an early response gene and induces a plethora of genes and signaling pathways. To identify robust signals in genes reliably upregulated by TNFα, we first measured microarray gene expression in vitro and searched methodologically comparable, publicly available data sets to identify concordant signals. Using tag single-nucleotide polymorphisms in the genes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Canada
Share to Datasets as Topic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interleukin-8

Share to Microarray Analysis

Share to Multiple Organ Failure

Share to NF-kappa B

Share to Randomized Controlled Trials as Topic

Share to Shock, Septic

Source

Open in PubMed Open full text

Identifiers

PMID: 26347487
DOI: 10.1159/000437330
PMCID: PMC6738761

Genes

TNFAIP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TNFAIP2 Inhibits Early TNFα-Induced NF-x03BA;B Signaling and Decreases Survival in Septic Shock Patients.PMID 26347487Read ↗

A single nucleotide polymorphism in NF-κB inducing kinase is associated with mortality in septic shock.Semantic proximity Read ↗

IL-1R2 as a Precision Therapeutic Target in Sepsis: Molecular Insights into Immune RegulationSemantic proximity Read ↗

Identification of haplotype tag single nucleotide polymorphisms within the nuclear factor-κB family genes and their clinical relevance in patients with major trauma.Semantic proximity Read ↗

Prediction of feature genes in trauma patients with the TNF rs1800629 A allele using support vector machine.Semantic proximity Read ↗

BCL2 genetic variants are associated with acute kidney injury in septic shock*.Semantic proximity Read ↗

Sepsis syndrome and death in trauma patients are associated with variation in the gene encoding tumor necrosis factor.Semantic proximity Read ↗

The TNF-α (-238 G/A) polymorphism could protect against development of severe sepsis.Semantic proximity Read ↗

OLFM4 polymorphisms predict septic shock survival after major surgery.Semantic proximity Read ↗

Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study.Semantic proximity Read ↗

Tumor necrosis factor gene polymorphism results in high TNF level in sepsis and septic shock.Semantic proximity Read ↗

Genetic variants in SERPINA4 and SERPINA5, but not BCL2 and SIK3 are associated with acute kidney injury in critically ill patients with septic shock.Semantic proximity Read ↗

Correlation Between Single Nucleotide Polymorphisms at the 3'-UTR of the NFKB1 Gene and Acute Kidney Injury in Sepsis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.