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Article

Genetic variants in SERPINA4 and SERPINA5, but not BCL2 and SIK3 are associated with acute kidney injury in critically ill patients with septic shock.

Critical care (London, England) - 8 Mar 2017

Vilander Laura M, Kaunisto Mari A, Vaara Suvi T, Pettilä Ville

Abstract excerpt

BACKGROUND: Acute kidney injury (AKI) is a multifactorial syndrome, but knowledge about its pathophysiology and possible genetic background is limited. Recently the first hypothesis-free genetic association studies have been published to explore individual susceptibility to AKI. We aimed to replicate the previously identified associations between five candidate single nucleotide polymorphisms (SNP) in...

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Identifiers

PMID: 28270177
DOI: 10.1186/s13054-017-1631-3
PMCID: PMC5341446

Genes

SERPINA4
SERPINA5
BCL2
SIK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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