Article
Frequency of SNP -336A/G in the promoter region of CD209 in a population from northeastern Brazil.
Genetics and molecular research : GMR - 14 Aug 2015
Costa P N, Ferreira-Fernandes H, de Oliveira J S, Pereira A C T C, Pinto G R, Ferreira G P
Abstract excerpt
Dendritic cells (DCs) mediate the initiation of the immune response against a variety of pathogens. The DC-SIGN receptor is encoded by the gene CD209 and is expressed on the surface of DCs. It binds to mannose-rich carbohydrates and enables the recognition of bacteria, fungi, parasites, and viruses. SNP -336A/G in the promoter region of CD209 influences the expression of the DC-SIGN receptor. Several studies have...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
