Article
DC-SIGN (CD209) promoter -336 A/G (rs4804803) polymorphism associated with susceptibility of Kawasaki disease.
TheScientificWorldJournal - 1 Jan 2012
Yu Hong-Ren, Chang Wei-Pin, Wang Lin, Lin Ying-Jui, Liang Chi-Di, Yang Kuender D, Kuo Chiu-Ming, Huang Yi-Chuan, Chang Wei-Chiao, Kuo Ho-Chang
Abstract excerpt
Kawasaki disease (KD) is characterized by systemic vasculitis of unknown etiology. High-dose intravenous immunoglobulin (IVIG) is the most effective therapy for KD to reduce the prevalence of coronary artery lesion (CAL) formation. Recently, the α2, 6 sialylated IgG was reported to interact with a lectin receptor, specific intracellular adhesion molecule-3 grabbing nonintegrin homolog-related 1 (SIGN-R1) in mice...
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