Article
Identification of residues important for substrate uptake in a glucose transporter from the filamentous fungus Trichoderma reesei.
Scientific reports - 8 Sept 2015
Zhang Weixin, Cao Yanli, Gong Jing, Bao Xiaoming, Chen Guanjun, Liu Weifeng
Abstract excerpt
The glucose transporter is an important player in cell metabolism that mediates the intracellular uptake of glucose. Here, we characterized the glucose transporter Stp1 from the filamentous fungus Trichoderma reesei. The individual substitution of several conserved residues for Ala in Stp1 corresponding to those interacting with D-glucose in the xylose/H(+) symporter XylE inflicted contrasting effects on its...
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