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Article

Functional Analysis of a Carotid Intima-Media Thickness Locus Implicates BCAR1 and Suggests a Causal Variant.

Circulation. Cardiovascular genetics - 1 Oct 2015

Boardman-Pretty Freya, Smith Andrew J P, Cooper Jackie, Palmen Jutta, Folkersen Lasse, Hamsten Anders, Catapano Alberico L, Melander Olle, Price Jacqueline F, Kumari Meena, Deanfield John E, Kivimäki Mika, Gertow Karl, Baragetti Andrea, Norata Giuseppe Danilo, Humphries Steve E

Abstract excerpt

BACKGROUND: Carotid intima-media thickness (IMT) is a marker of subclinical atherosclerosis that can predict cardiovascular disease events over traditional risk factors. This study examined the BCAR1-CFDP1-TMEM170A locus on chromosome 16, associated with carotid IMT and coronary artery disease in the IMT and IMT-Progression as Predictors of Vascular Events (IMPROVE) cohort, to identify the functional variant....

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Source

Identifiers

PMID: 26276885
DOI: 10.1161/CIRCGENETICS.115.001062

Genes

BCAR1
CFDP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional Analysis of a Carotid Intima-Media Thickness Locus Implicates BCAR1 and Suggests a Causal Variant.PMID 26276885Read ↗

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