Article
Potential for adaptation overrides cost of resistance.
Future microbiology - 1 Jan 2015
Moura de Sousa Jorge, Sousa Ana, Bourgard Catarina, Gordo Isabel
Abstract excerpt
AIM: To investigate the cost of antibiotic resistance versus the potential for resistant clones to adapt in maintaining polymorphism for resistance. MATERIALS & METHODS: Experimental evolution of Escherichia coli carrying different resistance alleles was performed under an environment devoid of antibiotics and evolutionary parameters estimated from their frequencies along time. RESULTS & CONCLUSION: Costly...
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