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Article

A distinct gene expression signature characterizes human neuroblastoma cancer stem cells.

Stem cell research - 1 Sept 2015

Ross Robert A, Walton Jeanette D, Han Dan, Guo Hong-Fen, Cheung Nai-Kong V

Abstract excerpt

Neuroblastoma, a malignancy of multipotent embryonic neural crest cells, is the most common extracranial solid cancer in childhood and most common cancer in infancy. Cellular phenotype has been shown to be an important determinant of the malignant potential in human neuroblastoma cells and tumors. Whereas neuroblastic (N-type) are moderately malignant and nonneuronal (S-type) cells are nonmalignant, I-type stem...

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Identifiers

PMID: 26342562
DOI: 10.1016/j.scr.2015.08.008
PMCID: PMC4601571

Genes

NOTCH1
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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