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Article

G-CSF receptor positive neuroblastoma subpopulations are enriched in chemotherapy-resistant or relapsed tumors and are highly tumorigenic.

Cancer research - 1 Jul 2013

Hsu Danielle M, Agarwal Saurabh, Benham Ashley, Coarfa Cristian, Trahan Denae N, Chen Zaowen, Stowers Paris N, Courtney Amy N, Lakoma Anna, Barbieri Eveline, Metelitsa Leonid S, Gunaratne Preethi, Kim Eugene S, Shohet Jason M

Abstract excerpt

Neuroblastoma is a neural crest-derived embryonal malignancy, which accounts for 13% of all pediatric cancer mortality, primarily due to tumor recurrence. Therapy-resistant cancer stem cells are implicated in tumor relapse, but definitive phenotypic evidence of the existence of these cells has be...

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Identifiers

PMID: 23687340
DOI: 10.1158/0008-5472.CAN-12-4056
PMCID: PMC4298227

Genes

STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23687340-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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