Article
Frequency of RANTES gene polymorphisms and their association with incidence of malaria: a longitudinal study on children in Iganga district, Uganda.
Malaria journal - 5 Sept 2015
Lwanira Catherine N, Mukasa Mark Kaddu, Swedberg Göte, Kironde Fred
Abstract excerpt
BACKGROUND: The severity and outcome of malaria is influenced by host immunity in which chemokines such as Regulated upon Activation, Normal T cell Expressed and Secreted (RANTES) play an important role. Previous studies show that variations in the RANTES gene affect RANTES protein production, hence altering host immunity. In this study, the relationship between presence of mutations in RANTES and incidence of...
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