Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases.

Abstract excerpt

Neurons are metabolically active cells with high energy demands at locations distant from the cell body. As a result, these cells are particularly dependent on mitochondrial function, as reflected by the observation that diseases of mitochondrial dysfunction often have a neurodegenerative component. Recent discoveries have highlighted that neurons are reliant particularly on the dynamic properties of...

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