Article
Novel plasminogen gene mutations in Turkish patients with type I plasminogen deficiency.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Sept 2016
Dönmez-Demir Buket, Celkan Tiraje, Sarper Nazan, Deda Gülhis, İnce Elif, Çalişkan Ümran, Öztürk Gülyüz, Karagün Barbaros, Küpesiz Alphan, Tokgöz Hüseyin, Akar Nejat, Özdağ Hilal
Abstract excerpt
The plasminogen (Plg) protein is the inactive proenzyme form of plasmin that dissolves fibrin thrombi by a process called fibrinolysis. It has been shown that homozygous or compound-heterozygous deficiency of this protein is a major cause of a rare inflammatory disease affecting mainly mucous membranes found in different body sites. In this study, five individual Turkish patients and nine Turkish families with...
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