Article
IDH1/2 mutation status combined with Ki-67 labeling index defines distinct prognostic groups in glioma.
Oncotarget - 6 Oct 2015
Zeng Ailiang, Hu Qi, Liu Yanwei, Wang Zheng, Cui Xiaoming, Li Rui, Yan Wei, You Yongping
Abstract excerpt
The current World Health Organization (WHO) classification of human gliomas is mainly based on morphology. However, it has limitations in prognostic prediction. We examined whether combining isocitrate dehydrogenase (IDH) 1/2 mutation status with the Ki-67 labeling index would improve the definition of prognostically distinct entities. We investigated the correlation of Ki-67 expression with IDH1/2 mutation...
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