Article
Genomic Prognosticators and Extent of Resection in Molecularly Subtyped World Health Organization Grade II and III Gliomas-A Single-Institution, Nine-Year Data.
World neurosurgery - 1 Jul 2021
Lasica Aleksandra B, Jaunmuktane Zane, Fersht Naomi, Kirkman Matthew A, Dixon Luke, Hoskote Chandrashekar, Brandner Sebastian, Samandouras George
Abstract excerpt
BACKGROUND: World Health Organization (WHO) grade II and III isocitrate dehydrogenase wild-type (IDH-wt) gliomas are often treated as WHO grade IV glioblastomas. However, cumulative evidence indicates that IDH mutation status alone is insufficient in predicting survival. The current study examines molecular and clinical markers to further prognostically stratify WHO grade II and III gliomas, in particular,...
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