Article
Engineered tobacco etch virus (TEV) protease active in the secretory pathway of mammalian cells.
Journal of biotechnology - 20 Oct 2015
Cesaratto Francesca, López-Requena Alejandro, Burrone Oscar R, Petris Gianluca
Abstract excerpt
Tobacco etch virus protease (TEVp) is a unique endopeptidase with stringent substrate specificity. TEVp has been widely used as a purified protein for in vitro applications, but also as a biological tool directly expressing it in living cells. To adapt the protease to diverse applications, several TEVp mutants with different stability and enzymatic properties have been reported. Herein we describe the development...
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