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Article

P1' specificity of the S219V/R203G mutant tobacco etch virus protease.

Proteins - 1 Sept 2024

Golda Mária, Hoffka Gyula, Cherry Scott, Tropea Joseph E, Lountos George T, Waugh David S, Wlodawer Alexander, Tőzsér József, Mótyán János András

Abstract excerpt

Proteases that recognize linear amino acid sequences with high specificity became indispensable tools of recombinant protein technology for the removal of various fusion tags. Due to its stringent sequence specificity, the catalytic domain of the nuclear inclusion cysteine protease of tobacco etch virus (TEV PR) is also a widely applied reagent for enzymatic removal of fusion tags. For this reason, efforts have...

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Identifiers

PMID: 38666764
DOI: 10.1002/prot.26693
PMCID: PMC11303109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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