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Article

High-resolution analysis of the human T-cell receptor repertoire.

Nature communications - 1 Sept 2015

Ruggiero Eliana, Nicolay Jan P, Fronza Raffaele, Arens Anne, Paruzynski Anna, Nowrouzi Ali, Ürenden Gökçe, Lulay Christina, Schneider Sven, Goerdt Sergij, Glimm Hanno, Krammer Peter H, Schmidt Manfred, von Kalle Christof

Abstract excerpt

Unbiased dissection of T-cell receptor (TCR) repertoire diversity at the nucleotide level could provide important insights into human immunity. Here we show that TCR ligation-anchored-magnetically captured PCR (TCR-LA-MC PCR) identifies TCR α- and β-chain diversity without sequence-associated or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26324409
DOI: 10.1038/ncomms9081
PMCID: PMC4569693

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26324409-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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