Article
Deregulation of TNF expression can also cause heart valve disease.
Cytokine - 1 Jan 2016
Lacey Derek, Bouillet Philippe
Abstract excerpt
High levels of the pro-inflammatory cytokine tumour necrosis factor (TNF) have been associated with many diseases including rheumatoid arthritis (RA), ankylosing spondylitis (AS), inflammatory bowel disease (IBD) and psoriasis. Although it has been clear for twenty-five years that TNF plays a major role in RA and AS, two major questions remain unanswered: (1) What mechanism underlies the loss of control of TNF...
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