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Article

Targeting sTNF/TNFR1 Signaling as a New Therapeutic Strategy

2015-03-06

Abstract excerpt

Deregulation of the tumor necrosis factor (TNF) plays an important role in the initiation and perpetuation of chronic inflammation and has been implicated in the development of various autoimmune diseases. Accordingly, TNF-inhibitors are successfully used for the treatment of several diseases, such as rheumatoid arthritis, inflammatory bowel disease, and psoriasis. However, total inhibition of TNF can cause severe...

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Identifiers and source

Literature Corpus work
65ce8610-6986-5358-aea9-260bdc508436
DOI
10.3390/antib4010048
Open publication

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Targeting sTNF/TNFR1 Signaling as a New Therapeutic StrategyDOI 10.3390/antib4010048
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