Article
Engineered strains of Streptococcus macedonicus towards an osmotic stress resistant phenotype retain their ability to produce the bacteriocin macedocin under hyperosmotic conditions.
Journal of biotechnology - 20 Oct 2015
Anastasiou Rania, Driessche Gonzalez Van, Boutou Effrossyni, Kazou Maria, Alexandraki Voula, Vorgias Constantinos E, Devreese Bart, Tsakalidou Effie, Papadimitriou Konstantinos
Abstract excerpt
Streptococcus macedonicus ACA-DC 198 produces the bacteriocin macedocin in milk only under low NaCl concentrations (<1.0%w/v). The thermosensitive plasmid pGh9:ISS1 was employed to generate osmotic stress resistant (osmr) mutants of S. macedonicus. Three osmr mutants showing integration of the ve...
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