Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Discovery of novel peptides regulating competence development in Streptococcus mutans.

Journal of bacteriology - 1 Nov 2014

Ahn Sang-Joon, Kaspar Justin, Kim Jeong Nam, Seaton Kinda, Burne Robert A

Abstract excerpt

A MarR-like transcriptional repressor (RcrR) and two predicted ABC efflux pumps (RcrPQ) encoded by a single operon were recently shown to be dominant regulators of stress tolerance and development of genetic competence in the oral pathogen Streptococcus mutans. Here, we focused on polar (ΔrcrR-P) and nonpolar (ΔrcrR-NP) rcrR mutants, which are hyper- and nontransformable, respectively, to dissect the mechanisms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Bacterial Proteins
Share to Base Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Codon, Initiator

Share to Gene Expression Regulation, Bacterial

Share to Open Reading Frames

Share to Streptococcus mutans

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 25135217
DOI: 10.1128/JB.01942-14
PMCID: PMC4248802

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Discovery of novel peptides regulating competence development in Streptococcus mutans.PMID 25135217Read ↗

Genome-Wide Screens Reveal New Gene Products That Influence Genetic Competence in Streptococcus mutans.Semantic proximity Read ↗

Conserved and divergent functions of RcrRPQ in Streptococcus gordonii and S. mutans.Semantic proximity Read ↗

Structure–Activity Relationships of the Competence Stimulating Peptide in Streptococcus mutans Reveal Motifs Critical for Membrane Protease SepM Recognition and ComD Receptor ActivationSemantic proximity Read ↗

Elucidating the Role of the Competence Regulon Quorum Sensing Circuitry in Streptococcus cristatusSemantic proximity Read ↗

An Essential Role for (p)ppGpp in the Integration of Stress Tolerance, Peptide Signaling, and Competence Development in Streptococcus mutansSemantic proximity Read ↗

Strategies to attenuate the competence regulon in Streptococcus pneumoniaeSemantic proximity Read ↗

A Novel Competence Pathway in the Oral Pathogen Streptococcus sobrinusSemantic proximity Read ↗

Competence Inhibition by the XrpA Peptide Encoded Within the <i>comX</i> Gene of <i>Streptococcus mutans</i>Semantic proximity Read ↗

A toxin/antitoxin system targeting the replication sliding-clamp induces competence in Streptococcus pneumoniaeSemantic proximity Read ↗

Transcriptome Analysis of Streptococcus mutans Quorum Sensing-Mediated Persisters Reveals an Enrichment in Genes Related to Stress Defense MechanismsSemantic proximity Read ↗

Effects of Carbohydrate Source on Genetic Competence in Streptococcus mutansSemantic proximity Read ↗

Investigating the Streptococcus sinensis competence regulon through a combination of transcriptome analysis and phenotypic evaluation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.