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Article

Heat resistance and salt hypersensitivity in Lactococcus lactis due to spontaneous mutation of llmg_1816 (gdpP) induced by high-temperature growth.

Applied and environmental microbiology - 1 Nov 2012

Smith William M, Pham Thi Huong, Lei Lin, Dou Junchao, Soomro Aijaz H, Beatson Scott A, Dykes Gary A, Turner Mark S

Abstract excerpt

During construction of several gene deletion mutants in Lactococcus lactis MG1363 which involved a high-temperature (37.5°C) incubation step, additional spontaneous mutations were observed which resulted in stable heat resistance and in some cases salt-hypersensitive phenotypes. Whole-genome sequencing of one strain which was both heat resistant and salt hypersensitive, followed by PCR and sequencing of four...

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Identifiers

PMID: 22923415
DOI: 10.1128/AEM.02316-12
PMCID: PMC3485701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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