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Article

Changes in the expression of Th17 cell-associated cytokines in the development of rheumatic heart disease.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology - 1 Jan 2000

Wen Yun, Zeng Zhiyu, Gui Chun, Li Lang, Li Wenting

Abstract excerpt

BACKGROUND: Autoimmunity plays a critical role in the development of rheumatic heart disease (RHD). Recent studies have linked Th17 cells to the autoimmune mechanism associated with RHD. This study aimed to investigate changes in Th17 cell-related cytokine expression in acute and chronic RHD. METHODS: We established a Lewis rat model of experimental RHD, which was induced by inactivated Group A streptococci and...

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Identifiers

PMID: 26318798
DOI: 10.1016/j.carpath.2015.07.006

Genes

RHD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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