Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TAGAP activates Th17 cell differentiation by promoting RhoA and NLRP3 to accelerate rheumatoid arthritis development

16 Jul 2023

Abstract excerpt

Rheumatoid arthritis (RA) is a chronic autoimmune disorder that can give rise to joint swelling and inflammation, potentially affecting the entire body, closely linked to the state of T cells. The T-cell activation Rho GTPase activating protein (TAGAP) is associated with many autoimmune diseases including RA and is directly linked to the differentiation of Th17 cells. The present study intends to investigate the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune and Inflammatory Disorders Research
Share to Immunodeficiency and Autoimmune Disorders
Share to Inflammasome and immune disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37458218
DOI: 10.1093/cei/uxad084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TAGAP activates Th17 cell differentiation by promoting RhoA and NLRP3 to accelerate rheumatoid arthritis developmentPMID 37458218Read ↗

T‐cell activation RhoGTPase‐activating protein plays an important role in TH17‐cell differentiationSemantic proximity Read ↗

Mechanism underlying the action of Duanteng-Yimu Tang in regulating Treg/Th17 imbalance and anti-rheumatoid arthritisSemantic proximity Read ↗

An Update on the Emerging Role of Wnt/β-catenin, SYK, PI3K/AKT, and GM-CSF Signaling Pathways in Rheumatoid ArthritisSemantic proximity Read ↗

Exploring the therapeutic potential of regulatory T cell in rheumatoid arthritis: Insights into subsets, markers, and signaling pathwaysSemantic proximity Read ↗

Function and Role of Regulatory T Cells in Rheumatoid Arthritis.Semantic proximity Read ↗

The Therapeutic Potential of Phytochemicals Unlocks New Avenues in the Management of Rheumatoid ArthritisSemantic proximity Read ↗

Natural killer-like B cells promote Th17 cell differentiation and exacerbate rheumatoid arthritisSemantic proximity Read ↗

Tripterine ameliorates monosodium urate crystal-induced gouty arthritis by altering macrophage polarization via the miR-449a/NLRP3 axis.Semantic proximity Read ↗

Molecular mechanisms underpinning T helper 17 cell heterogeneity and functions in rheumatoid arthritis.Semantic proximity Read ↗

New classification of rheumatoid arthritis based on immune cells and clinical characteristicsSemantic proximity Read ↗

Are Th17 cells an appropriate new target in the treatment of rheumatoid arthritis?Semantic proximity Read ↗

Exploring the molecular mechanisms of the involvement of GZMB-Caspase-3-GSDME pathway in the progression of rheumatoid arthritisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.