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Article

Simultaneous detection of human papillomavirus integration and c-MYC gene amplification in cervical lesions: an emerging marker for the risk to progression.

Archives of gynecology and obstetrics - 1 Apr 2016

Gimenes Fabrícia, Souza Raquel Pantarotto, de Abreu André Luelsdorf Pimenta, Pereira Monalisa Wolski, Consolaro Marcia Edilaine Lopes, da Silva Vânia Ramos Sela

Abstract excerpt

PURPOSE: The persistence of high-risk oncogenic human papillomavirus (HR-HPV) infection and its integration into the host genome are key steps in the induction of malignant alterations. c-MYC chromosome region is a frequent localization for HPV insertion that has been observed in chromosome band 8q24 by fluorescence in situ hybridization (FISH). We report the HPV viral integration and amplification patterns of...

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PMID: 26315473
DOI: 10.1007/s00404-015-3870-3

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MYC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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