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Article

NKX6.3 controls gastric differentiation and tumorigenesis.

Oncotarget - 29 Sept 2015

Yoon Jung Hwan, Choi Won Suk, Kim Olga, Choi Sung Sook, Lee Eun Kyung, Nam Suk Woo, Lee Jung Young, Park Won Sang

Abstract excerpt

NKX6.3 transcription factor is known to be an important regulator in gastric mucosal epithelial differentiation. The present study aimed to investigate whether NKX6.3 acts as an essential tumor suppressor in gastric carcinogenesis. Absent or reduced protein expression and decreased DNA copy numbe...

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Share to CDX2 Transcription Factor
Share to Cell Cycle Checkpoints
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastric Mucosa

Share to Immunoblotting

Share to Peptide Hormones

Share to SOXB1 Transcription Factors

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Source

Open in PubMed Open full text

Identifiers

PMID: 26314965
DOI: 10.18632/oncotarget.4952
PMCID: PMC4695069

Genes

GKN1
CDX2
SOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26314965-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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NKX6.3 controls gastric differentiation and tumorigenesis.PMID 26314965Read ↗

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