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Article

Genetic variants of CD160, MERTK, and IL15 in natural killer cell-related pathway predict gastric cancer survival.

Frontiers in immunology - 1 Jan 2026

Zeng Guang, Lu Guoqiang, Hu Beiping, Xu Midie, Li Guanlin, Wang Mengyun, Qiu Lixin, Zhang Ruoxin, Cheng Lei, Xu Wanghong, Liu Xiaowen, Jin Guangfu, Liu Hongliang, Wei Qingyi

Abstract excerpt

Background: Natural killer (NK) cells play a pivotal role in anti-tumor immunity; however, the prognostic significance of genetic variants in NK cell-related genes in gastric cancer (GC) remains largely uncertain. Methods: We systematically evaluated 12,476 single-nucleotide polymorphisms (SNPs) in 151 NK cell-related genes for their associations with overall survival (OS) in 2,211 Chinese GC patients with...

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Share to Antigens, CD
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42064062
DOI: 10.3389/fimmu.2026.1765825
PMCID: PMC13125121

Genes

GC
CD160
IL15
MERTK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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