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Article

Identification of FOXO3 and PRDM1 as tumor-suppressor gene candidates in NK-cell neoplasms by genomic and functional analyses.

Blood - 22 Sept 2011

Karube Kennosuke, Nakagawa Masao, Tsuzuki Shinobu, Takeuchi Ichiro, Honma Keiichiro, Nakashima Yasuhiro, Shimizu Norio, Ko Young-Hyeh, Morishima Yasuo, Ohshima Koichi, Nakamura Shigeo, Seto Masao

Abstract excerpt

Oligo-array comparative genomic hybridization (CGH) and gene-expression profiling of natural killer (NK)-cell neoplasms were used in an effort to delineate the molecular pathogenesis involved. Oligo-array CGH identified two 6q21 regions that were most frequently deleted (14 of 39 or 36%). One of...

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Share to Comparative Genomic Hybridization
Share to Forkhead Box Protein O3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Killer Cells, Natural

Share to Leukemia, Large Granular Lymphocytic

Share to Lymphoma, Follicular

Share to Positive Regulatory Domain I-Binding Factor 1

Share to Retroviridae

Share to Transduction, Genetic

Source

Identifiers

PMID: 21690554
DOI: 10.1182/blood-2011-04-346890

Genes

PRDM1
FOXO3
POPDC3
ATG5
PREP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21690554-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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