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Article

Zn(II)-curc targets p53 in thyroid cancer cells.

International journal of oncology - 1 Oct 2015

Garufi Alessia, D'Orazi Valerio, Crispini Alessandra, D'Orazi Gabriella

Abstract excerpt

TP53 mutation is a common event in many cancers, including thyroid carcinoma. Defective p53 activity promotes cancer resistance to therapies and a more malignant phenotype, acquiring oncogenic functions. Rescuing the function of mutant p53 (mutp53) protein is an attractive anticancer therapeutic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26314369
DOI: 10.3892/ijo.2015.3125
PMCID: PMC4583539

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26314369-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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