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Article

Dissecting the role of epidermal growth factor receptor catalytic activity during liver regeneration and hepatocarcinogenesis

27 Aug 2015

Abstract excerpt

UNLABELLED: Different data support a role for the epidermal growth factor receptor (EGFR) pathway during liver regeneration and hepatocarcinogenesis. However, important issues, such as the precise mechanisms mediating its actions and the unique versus redundant functions, have not been fully defined. Here, we present a novel transgenic mouse model expressing a hepatocyte-specific truncated form of human EGFR,...

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Share to Cytokine Signaling Pathways and Interactions
Share to Hepatocellular Carcinoma Treatment and Prognosis
Share to Liver physiology and pathology

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PMID: 26313466
DOI: 10.1002/hep.28134

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