Article
[HLA alleles association and recurrent spontaneous abortion in a São Luis/Maranhão population, in Brazilian Northeastern region].
Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia - 1 Aug 2015
Silva Fábio França, Mesquita Emygdia Rosa Rêgo Barros Pires Leal, Patricio Fernando José Brito, Corrêa Rita da Graça Carvalhal Frazão, Ferreira Evaldo César Macau Furtado, Chein Maria Bethânia da Costa, Brito Luciane Maria Oliveira
Abstract excerpt
PURPOSE: To investigate the association of the HLA-A, -B and -DRB1 alleles with the occurrence of Recurrent Spontaneous Abortion. METHODS: A case-control study of 200 women aged 18 to 35 years, consisting of a convenience sample of 100 women who had idiopathic recurrent spontaneous abortion and 100 women without abortion and with two or more children. Peripheral blood genomic DNA was extracted from 500l of Buffy...
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